Histone Deacetylase Pathway

Local business

45-1 Ramsey Road, Shirley, NY 11967, USA
11967 Shirley
USA

The orderly regulation of gene transcription is a prerequisite for the maintenance of normal functions of the body's cells. If the transcriptional regulation of the gene is disordered, the cells may become cancerous. Recent studies have found that the occurrence of tumors is closely related to the imbalance between acetylation and deacetylation of core histones. In the organism, a pair of functionally antagonistic proteases is responsible for histone acetylation and deacetylation, namely histone acetyltransferase (HAT) and histone deacetylase (HDAC).

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