Chk Signaling Pathway

Local business

45-1 Ramsey Road, Shirley, NY 11967, USA
11967 Shirley
USA

The role of the cell cycle checkpoint kinase is to maintain the genome's fidelity by blocking the cell cycle and repairing damaged DNA after DNA damage. Known cell cycle checkpoint kinases include: Chk1 (checkpoint kinase 1) and Chk2 (checkpoint kinase 2). Both of them have overlapping substrate profiles and similar structures but are not expressed equally in cells and tissues of different tumors and other diseases.

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